
Stachyose Tetrahydrate (CAS 10094-58-3) Now Available: High-Purity Prebiotic for Gut Health & Functional Food
What Is Stachyose Tetrahydrate?
Stachyose tetrahydrate (C₂₄H₄₂O₂₁·4H₂O, MW 738.64) is the hydrated form of stachyose, a non-reducing tetrasaccharide composed of two α-D-galactose units, one α-D-glucose and one β-D-fructose, linked by α(1->6) and α(1->2) glycosidic bonds[1](@ref). It occurs naturally in Chinese artichoke (Stachys tuberifera), soybeans, mung beans and other legumes.
Key biochemical traits:
– Mild natural sweetness, clean taste profile
– Passes undigested through upper GI; fermented selectively in the colon
– Promotes proliferation of Bifidobacterium & Lactobacillus, suppresses Clostridium spp.
– Produces SCFAs (acetate, propionate, butyrate), lowers colonic pH
– Reported in vitro: dose-dependent inhibition of Caco-2 proliferation & induction of apoptosis[7](@ref)
Stachyose tetrahydrate is therefore positioned as:
– A prebiotic dietary fiber (raffinose-family oligosaccharide)
– A functional food / beverage sweetener-fiber dual-ingredient
– A fermentation carbon source for probiotic / enzyme / organic-acid industries
– A research reagent (gut microbiome, carbohydrate metabolism)
Application Scenarios
- Functional Food & Beverage
– Dairy: yogurt, cheese, formulated milk powder (0.5 – 2.0%)[3](@ref)
– Plant-based beverages, juice, protein drinks
– Bakery: bread / cake / biscuit, partial sucrose replacement (1.0 – 3.0%)[3](@ref)
– Confectionery: gummy, hard candy (1.0 – 4.0%)
– Seasoning & sauces (0.5 – 1.5%)
– Role: prebiotic fiber + mild sweetness + moisture retention
- Dietary Supplements / Probiotic Formulations
– Synbiotic blends (Stachyose + Bifido / Lacto strains)
– Gut-health capsules, powders, sachets
– Pediatric / elderly nutrition (soft stool, microbiota modulation)
- Animal Feed Additive
– Swine / poultry / aquaculture: improves FCR via gut flora modulation
– Reduces ammonia emission, replaces antibiotic growth promoters (AGP-free formulas)
- Fermentation Industry Carbon Source
– Carbon for enzyme (amylase, protease), organic acid (lactic, citric), probiotic biomass production[3](@ref)
- Research Use
– Gut microbiome in vitro models (SHIME®, batch fermentation)
– Caco-2 / colon cancer cell studies
– Carbohydrate metabolism, α-galactosidase induction assays[7](@ref)